职称：二级教授/一级主任医师
联系电话：13808628560
电子邮箱：xiazhongyuan2005@aliyun.com
个人简介
医学博士，二级教授，一级主任医师，博士生导师，加拿大UBC大学访问学者。武汉大学人民医院麻醉科主任、学科带头人，武汉大学第一临床学院麻醉教研室主任，湖北省医学领军人才，湖北省医德楷模，湖北省五一劳动奖章获得者，湖北省干部保健工作先进工作者，国内知名麻醉学中青年专家。
任教育部高等学校临床医学类专业教学指导委员会麻醉学专业教学指导分委员会副主任委员，中国医药教育协会麻醉专业委员会副主任委员，中国医师协会麻醉学分会常务委员，中华医学会麻醉学分会委员，心胸麻醉学学组副组长，中国心胸血管麻醉学会常务委员，中国研究型医院学会麻醉学专业委员会常务委员，湖北省医学会麻醉学分会第八届主任委员，湖北省医学会/武汉市医学会理事、武汉市医学会麻醉学分会第十届主任委员。任《中华麻醉学杂志》、《临床麻醉学杂志》、《武汉大学学报（医学版）》、《国际麻醉学与复苏杂志》等杂志编委。
主持或参与制定《围术期患者低体温防治专家共识》、《老年患者非心脏手术围术期肾脏损伤防治专家共识(2022版)》、《Recommendations on perioperative management and emergency intubation for patients with Omicron》、《围术期中心静脉监测的专家共识》、《术后胃肠功能障碍防治专家共识（2021年）》、《冠心病患者非心脏手术麻醉及围术期管理的专家共识》、《宫腔镜诊疗麻醉管理的专家共识》等专家共识。全年完成各类危重手术比例达90%，每年参加省内危重手术的麻醉会诊/抢救100例以上，并在省内推广围术期高危病人重要脏器保护综合策略，使严重并发症下降75%，获同行专家认可。
主持国家自然科学基金面上项目7项，参与国家自然科学基金面上项目多项，主持省重点课题1项，参与2021 国家重点研发计划1项，国际横向合作课题1项，主持省基金3项。其研究成果获湖北省科技进步二等奖2项（第一完成人）、湖北省科技成果推广二等奖1项（第一完成人）、内蒙古自治区科学技术进步奖一等奖。出版及参编专著10部、专利10项；以第一作者/通讯作者发表论文近300余篇，其中SCI论文近80余篇，包括国际TOP期刊EClinicalMedicine、Free Radic Biol Med、Cell Death & Disease、Crit Care Med等，其学术影响力在“全国麻醉医学领域学者学术影响力排名（2018-2022）”排行榜居全国第2，创造历史最高成就；在“全国麻醉医学领域学者学术影响力排名（2012-2021）”排行榜居全国第4；在“2020年度中国麻醉领域高价值国际论文”排行榜中居第3。
在人才培养方面，已培养博士和硕士98人，正在培养博士、硕士研究生20余人，培养进修医生200余人，在保证培养数量的同时更是保证培养的质量，所培养的学生受到用人单位广泛的好评，就业分布不仅仅局限在湖北省，而是分布在全国各地，包括河南、江苏、福建、山东、广东、海南、内蒙古等十余个省市自治区，且培养的学生每年有2-3位优秀青年获得国家自然科学基金面上或青年基金，其中培养的部分学生成为湖北省第二届医学青年拔尖人才1人、省内学会常委9人、湖北省/各地主委和学科带头人8人、院长和科主任13人。
研究方向
1. 糖尿病心肌缺血再灌注损伤机制研究；2. 围术期脏器保护
发表论文
SCI
1. Li W, Leng Y, Xiong Y, Li W, Cai Y, Xue R, Chen R, Lei S, Xia Z, Xia Z. DJ-1 preserves ischemic postconditioning-induced cardioprotection in STZ-induced type 1 diabetic rats: role of PTEN and DJ-1 subcellular translocation.Cell Commun Signal. 2024; 22(1): 252.
2. Gao S, Zhao X, Leng Y, Xia Z. Dietary supplementation with inulin improves burn-induced skeletal muscle atrophy by regulating gut microbiota disorders.Sci Rep. 2024; 14(1): 2328.
3. Chen L, Wu K, He J, Hou J, Zhang Y, Liu L, Wang J, Xia Z. Circadian Regulation of the Lactate Metabolic Kinetics in Mice Using the [1H-13C]-NMR Technique. Mol Neurobiol. 2024; Epub.
4. Wu H, Wang L, Kang P, Zhou X, Li W, Xia Z.The SP1/SIRT1/ACLY signaling axis mediates fatty acid oxidation in renal ischemia-reperfusion-induced renal fibrosis.Int Immunopharmacol. 2024; 132: 112002.
5. Zhou L, Zhu X, Lei S, Wang Y, Xia Z. The role of the ER stress sensor IRE1 in cardiovascular diseases.Mol Cell Biochem. 2024; Epub.
6. Tian H, Zhao X, Zhang Y, Xia Z. Research progress of circadian rhythm in cardiovascular disease: A bibliometric study from 2002 to 2022. Heliyon. 2024; 10(7): e28738.
7. Wu B, Xu C, Xu C, Qiu L, Gao JX, Li M, Xiong Y, Xia H, Xia Z, Liu X. Inhibition of Sema4D attenuates pressure overload-induced pathological myocardial hypertrophy via the MAPK/NF-κB/NLRP3 pathways.Biochim Biophys Acta Mol Basis Dis. 2024; 1870(3): 166944.
8. Zhou L, Su W, Wang Y, Zhang Y, Xia Z, Lei S. FOXO1 reduces STAT3 activation and causes impaired mitochondrial quality control in diabetic cardiomyopathy.Diabetes Obes Metab. 2024; 26(2): 732-744.
9. Tian H, Huang Q, Cheng J, Xiong Y, Xia Z. Rev-erbα attenuates diabetic myocardial injury through regulation of ferroptosis.Cell Signal. 2024;114:111006.
10. Ding H, Xiang R, Jia Y, Ye J, Xia Z. Cyclosporin A-mediated translocation of HuR improves MTX-induced cognitive impairment in a mouse model via NCOA4-mediated ferritinophagy. Aging (Albany NY). 2023; 15(21): 12537-12550.
11. Xiong Y, Leng Y, Li W, Li W, Tian H, Tao J, Chen R, Xia Z. Nogo-A Mediated Endoplasmic Reticulum Stress During Myocardial Ischemic-Reperfusion Injury in Diabetic Rats. Cardiovasc Toxicol. 2023; 23(3-4): 147-160.
12. Wu K, Chen L, Qiu Z, Zhao B, Hou J, Lei S, Jiang M, Xia Z. Protective Effect and Mechanism of Xbp1s Regulating HBP/O-GlcNAcylation through GFAT1 on Brain Injury after SAH. Biomedicines. 2023; 11(5): 1259.
13. Zhou L, Su W, Wang Y, Zhang Y, Xia Z, Lei S. FOXO1 reduces STAT3 activation and causes impaired mitochondrial quality control in diabetic cardiomyopathy.Diabetes Obes Metab. 2024; 26(2): 732-744.
14. Wang W, Zhao B, Gao W, Song W, Hou J, Zhang L, Xia Z. Inhibition of PINK1-Mediated Mitophagy Contributes to Postoperative Cognitive Dysfunction through Activation of Caspase-3/GSDME-Dependent Pyroptosis.ACS Chem Neurosci. 2023; 14(7): 1249-1260.
15. Yuan M, Jing G, Kong Q, Ming T, Zuo J, Wang Q, Feng Y, Liu W, Wu X, Xia Z. TIPE2 ameliorates neuroinflammation and cognitive impairment in sepsis-associated encephalopathy through regulating RhoA/ROCK2-NF-κB signaling pathway.Biochem Pharmacol. 2023; 217: 115816.
16. Huang Q, Tian H, Tian L, Zhao X, Li L, Zhang Y, Qiu Z, Lei S, Xia Z. Inhibiting Rev-erbα-mediated ferroptosis alleviates susceptibility to myocardial ischemia-reperfusion injury in type 2 diabetes. Free Radic Biol Med. 2023; 209: 135-150.
17. Zhu XZ, Qiu Z, Lei SQ, Leng Y, Li WY, Xia ZY. The Role of P53 in Myocardial Ischemia-Reperfusion Injury.Cardiovasc Drugs Ther. 2023.
18. SNAP25 ameliorates postoperative cognitive dysfunction by facilitating PINK1-dependent mitophagy and impeding caspase-3/GSDME-dependent pyroptosis.Wang W, Gao W, Zhang L, Xia Z, Zhao B. Exp Neurol. 2023; 367: 114463.
19. Xiong Y, Leng Y, Tian H, Deng X, Li W, Li W, Xia Z. Decreased MFN2 activates the cGAS-STING pathway in diabetic myocardial ischaemia-reperfusion by triggering the release of mitochondrial DNA. Cell Commun Signal. 2023; 21(1): 192.
20. Huang Q, Tian L, Zhang Y, Qiu Z, Lei S, Xia ZY. Nobiletin alleviates myocardial ischemia-reperfusion injury via ferroptosis in rats with type-2 diabetes mellitus. Biomed Pharmacother. 2023; 163: 114795.
21. Wang W, Huo P, Zhang L, Lv G, Xia Z. Decoding competitive endogenous RNA regulatory network in postoperative cognitive dysfunction. Front Neurosci. 2022; 16: 972918.
22. Yang Y, Xia Z, Xu C, Zhai C, Yu X, Li S. Ciprofol attenuates the isoproterenol-induced oxidative damage, inflammatory response and cardiomyocyte apoptosis. Front Pharmacol. 2022; 13: 1037151.
23. Tian H, Xiong Y, Xia Z. Resveratrol ameliorates myocardial ischemia/reperfusion induced necroptosis through inhibition of the Hippo pathway. J Bioenerg Biomembr. 2023; 55(1): 59-69.
24. Ye J, Chen J, Wang J, Xia Z, Jia Y. Association of the Timeless Gene with Prognosis and Clinical Characteristics of Human Lung Cancer. Diagnostics(Basel). 2022; 12(11): 2681.
25. Xu C, Zhu Y, Wu L, Yu H, Liu J, Zhou F, Xiong Q, Wang S, Cui S, Huang X, Yin A, Xu T, Lei S, Xia Z. Evaluating the effect of an artificial intelligence system on the anesthesia quality control during gastrointestinal endoscopy with sedation: a randomized controlled trial. BMC Anesthesiol. 2022; 22(1): 313.
26. Li W, Xia Z, Wang Y. A Bibliometric Analysis of Publications on Ferritinophagy from 2014 to 2021. Front Biosci (Landmark Ed). 2022; 27(6): 193.
27. Li L, Lin L, Lei S, Shi S, Chen C, Xia Z. Maslinic Acid Inhibits Myocardial Ischemia-Reperfusion Injury-Induced Apoptosis and Necroptosis via Promoting Autophagic Flux. DNA Cell Biol. 2022; 41(5): 487-497.
28. Wang W, Huo P, Wang E, Song W, Huang Y, Liu Z, Zhao B, Xia Z. Dexmedetomidine infusion for emergence coughing prevention in patients undergoing an endovascular interventional procedure: A randomized dose-finding trial. Eur J Pharm Sci. 2022; 177: 106230.
29. Ming T, Dong M, Song X, Li X, Kong Q, Fang Q, Wang J, Wu X, Xia Z. Integrated Analysis of Gene Co-Expression Network and Prediction Model Indicates Immune-Related Roles of the Identified Biomarkers in Sepsis and Sepsis-Induced Acute Respiratory Distress Syndrome. Front Immunol. 2022; 13: 897390.
30. Chen J, Liu C, Xu M, Zhu J, Xia Z. Upregulation of miR-19b-3p exacerbates chronic stress-induced changes in synaptic plasticity and cognition by targeting Drebrin. Neuropharmacology. 2022; 207: 108951.
31. Huang Q, Jiang M, Xia ZY, Lei S, Zhao B, Qiu Z. Role of CK1ε-regulated PERIOD2 in STZ-induced diabetic myocardial injury. Front Biosci (Landmark Ed). 2022; 27(2): 58.
32. Qiao Q, Fu X, Huang R, Lei S, Leng Y, Liu Z, Xia Z, Jiang X. Ropivacaine-loaded, hydroxypropyl chitin thermo-sensitive hydrogel combined with hyaluronan: an injectable, sustained-release system for providing long-lasting local anesthesia in rats. Reg Anesth Pain Med. 2022; 47(4): 234-241.
33. Qiu Z, Ming H, Zhang Y, Yu Y, Lei S, Xia ZY. The Protective Role of Bmal1-Regulated Autophagy Mediated by HDAC3/SIRT1 Pathway in Myocardial Ischemia/Reperfusion Injury of Diabetic Rats. Cardiovasc Drugs Ther. 2022. 36(2): 229-243.
34. Tian H, Xiong Y, Zhang Y, Leng Y, Tao J, Li L, Qiu Z, Xia Z. Activation of NRF2/FPN1 pathway attenuates myocardial ischemia-reperfusion injury in diabetic rats by regulating iron homeostasis and ferroptosis. Cell Stress Chaperones. 2021.27(2): 149-164.
35. Chen J, Li X, Jia Y, Xia Z, Ye J. Publication Trends on Mitophagy in the World and China: A 16-Year Bibliometric Analysis. Front Cell Dev Biol. 2021; 9: 793772.
36. Li W, Li W, Wang Y, Leng Y, Xia Z. Inhibition of DNMT-1 alleviates ferroptosis through NCOA4 mediated ferritinophagy during diabetes myocardial ischemia/reperfusion injury. Cell Death Discov. 2021; 7(1): 267.
37. Liu L, Cao Q, Gao W, Li B, Xia Z, Zhao B. Melatonin protects against focal cerebral ischemia- reperfusion injury in diabetic mice by ameliorating mitochondrial impairments: involvement of the Akt-SIRT3-SOD2 signaling pathway. Aging (Albany NY). 2021; 13(12): 16105-16123.
38. Chen R, Li W, Qiu Z, Zhou Q, Zhang Y, Li WY, Ding K, Meng QT, Xia ZY. Ischemic Postconditioning-Mediated DJ-1 Activation Mitigate Intestinal Mucosa Injury Induced by Myocardial Ischemia Reperfusion in Rats Through Keap1/Nrf2 Pathway. Front Mol Biosci. 2021; 8 : 655619.
39. Yang Z, Su W, Zhang Y, Zhou L, Xia ZY, Lei S. Selective inhibition of PKCβ2 improves Caveolin-3/eNOS signaling and attenuates lipopolysaccharide-induced injury by inhibiting autophagy in H9C2 cardiomyocytes. J Mol Histol. 2021; 52(4):705-715.
40. Chen J, Wang J, Li C, Ding H, Ye J, Xia Z. Dexmedetomidine reverses MTX-induced neurotoxicity and inflammation in hippocampal HT22 cell lines via NCOA4-mediated ferritinophagy. Aging (Albany NY). 2021; 13(4): 6182-6193.
41. Deng L, Lei S, Wang X, Jiang F, Lubarsky DA, Zhang L, Liu D, Han C, Zhou D, Wang Z, Sun X, Zhang Y, Cheung CW, Wang S, Xia Z, Applegate RL, Tang J, Mai Z, Liu H, Xia Z. Course of illness and outcomes in older COVID-19 patients treated with HFNC: a retrospective analysis. Aging (Albany NY). 2021; 13(12):15801-15814.
42. Chen H, Song W, Wang W, Peng Y, Zhai C, Yao L, Xia Z. Ultrasound-guided parasternal intercostal nerve block for postoperative analgesia in mediastinal mass resection by median sternotomy: a randomized, double-blind, placebo-controlled trial. BMC Anesthesiol. 2021; 21(1): 98.
43. Leng Y, Chen M, Dai M, Wu Y, Lei SQ, Yan K, Shao NY, Xia Z, Liu M. Minimized glycemic fluctuation decreases the risk of severe illness and death in patients with COVID-19. J Med Virol. 2021; 93(7): 4060-4062.
44. Qiu Z, Ming H, Lei S, Zhou B, Zhao B, Yu Y, Xue R, Xia Z. Roles of HDAC3-orchestrated circadian clock gene oscillations in diabetic rats following myocardial ischaemia/reperfusion injury. Cell Death Dis. 2021; 12(1): 43.
45. Pan X, Shen C, Huang Y, Wang L, Xia Z. Corrigendum to "Loss of SNHG4 Attenuated Spinal Nerve Ligation-Triggered Neuropathic Pain through Sponging miR-423-5p". Mediators Inflamm. 2020; 2020: 6369898.
46. Su W, Qiu Z, Zhou L, Hou J, Wang Y, Huang F, Zhang Y, Jia Y, Zhou J, Liu D, Xia Z, Xia ZY, Lei S. Sex differences in clinical characteristics and risk factors for mortality among severe patients with COVID-19: a retrospective study. Aging (Albany NY). 2020; 12(19): 18833-18843.
47. Fang S, Wang H, Lu L, Jia Y, Xia Z. Decreased complement C3 levels are associated with poor prognosis in patients with COVID-19: A retrospective cohort study. Int Immunopharmacol. 2020; 89(Pt A): 107070.
48. Huang L, Fang HB, Cheng HH, Mei SL, Cheng YP, Lv Y, Meng QT, Xia ZY. Epigenetic modulation of the MAPK pathway prevents isoflurane-induced neuronal apoptosis and cognitive decline in aged rats. Exp Ther Med. 2020; 20(5): 35.
49. Hu YD, Tang CL, Jiang JZ, Lv HY, Wu YB, Qin XD, Shi S, Zhao B, Zhu XN, Xia ZY. Neuroprotective Effects of Dexmedetomidine Preconditioning on Oxygen-glucose Deprivation-reoxygenation Injury in PC12 Cells via Regulation of Ca2+-STIM1/Orai1 Signaling. Curr Med Sci. 2020; 40(4): 699-707.
50. Wang W, Song W, Xia Z, He Y, Tang L, Hou J, Lei S. Sleep Disturbance and Psychological Profiles of Medical Staff and Non-Medical Staff During the Early Outbreak of COVID-19 in Hubei Province, China. Front Psychiatry. 2020; 11: 733.
51. Zhang A, Leng Y, Zhang Y, Wu K, Ji Y, Lei S, Xia Z. Meta-Analysis of coagulation parameters associated with disease severity and poor prognosis of COVID-19. Int J Infect Dis. 2020: 100:441-448.
52. Ming T, Yuan M, Kong Q, Huang Q, Xia Z, Wu X. Dexmedetomidine alleviates blunt chest trauma and hemorrhagic shock‑resuscitation‑induced acute lung injury through inhibiting the NLRP3 inflammasome. Mol Med Rep. 2020; 22(3):2507-2515.
53. Yang Y, Xu C, Tang S, Xia Z.Interleukin-9 Aggravates Isoproterenol-Induced Heart Failure by Activating Signal Transducer and Activator of Transcription 3 Signalling. Can J Cardiol. 2020; 36(11): 1770-1781.
54. Song WQ, Wang W, Yang YC, Sun Q, Chen H, Zhang L, Bu XS, Zhan LY, Xia ZY. Parasternal Intercostal Block Complementation Contributes to Postoperative Pain Relief in Modified Radical Mastectomy Employing Pectoral Nerve Block I and Serratus-Intercostal Block: A Randomized Trial. J Pain Res. 2020; 13: 865-871.
55. Pan X, Shen C, Huang Y, Wang L, Xia Z. Loss of SNHG4 Attenuated Spinal Nerve Ligation-Triggered Neuropathic Pain through Sponging miR-423-5p. Mediators Inflamm. 2020; 2020: 2094948.
56. Li W, Li W, Leng Y, Xiong Y, Xue R, Chen R, Xia Z. Mechanism of N-acetylcysteine in alleviating diabetic myocardial ischemia reperfusion injury by regulating PTEN/Akt pathway through promoting DJ-1. Biosci Rep. 2020; BSR20192118.
57. Lei S, Jiang F, Su W, Chen C, Chen J, Mei W, Zhan LY, Jia Y, Zhang L, Liu D, Xia ZY, Xia Z. Clinical characteristics and outcomes of patients undergoing surgeries during the incubation period of COVID-19 infection. EClinicalMedicine. 2020; 100331
58. Zeng C, Sun Q, Meng QT, Xia ZY, Xiao YD. Effects of ATRA on diabetic rats with renal ischemia-reperfusion injury. Acta Cir Bras. 2020; 35(1): e202000106.
59. Kong Q, Wu X, Qiu Z, Huang Q, Xia Z, Song X. Protective Effect of Dexmedetomidine on Acute Lung Injury via the Upregulation of Tumour Necrosis Factor-α-Induced Protein-8-like 2 in Septic Mice. Inflammation. 2020; 43(3): 833-846.
60. Li W, Li W, Leng Y, Xiong Y, Xia Z. Ferroptosis Is Involved in Diabetes Myocardial Ischemia/Reperfusion Injury Through Endoplasmic Reticulum Stress. DNA Cell Biol. 2020; 39(2): 210-225.
61. Zhou B, Yu YL, Qiu Z, Meng QT, Xia ZY. GDF11 ameliorated myocardial ischemia reperfusion injury by antioxidant stress and up-regulating autophagy in STZ-induced type 1 diabetic rats. Acta Cir Bras. 2020; 34(11): e201901106.
62. Liu K, Huang YY, Zhou F, Zhao B, Xia ZY. Dexmedetomidine attenuates P2X4 and NLRP3 expression in the spine of rats with diabetic neuropathic pain. Acta Cir Bras.2019;34(11): e201901105.
63. Nuo M, Sen Ta Na H, Meng QT, Xia ZY. Propofol alleviates oxidative stress via upregulating lncRNA-TUG1/Brg1 pathway in hypoxia/reoxygenation hepatic cells. J Biochem. 2019;166(5): 415-421.
64. Ha Sen Ta Na, Nuo M, Meng QT, Xia ZY. The Pathway of Let-7a-1/2-3p and HMGB1 Mediated Dexmedetomidine Inhibiting Microglia Activation in Spinal Cord Ischemia- Reperfusion Injury Mice. J Mol Neurosci. 2019;69(1):106-114.
65. Zhong HY, Yang Z, Qiu Z, Lei SQ, Xia ZY. The neuroprotective mechanism of 2-arachidonoylglycerol 2-AG against non-caspase-dependent apoptosis in mice hippocampal neurons following MCAO. Neuropsychiatr Dis Treat. 2019;15: 2417-2424.
66. Wang W, Song W, Yang C, Sun Q, Chen H, Zhang L, Bu X, Zhan L, Xia Z. Ultrasound- Guided Pectoral Nerve Block I and Serratus-Intercostal Plane Block Alleviate Postoperative Pain in Patients Undergoing Modified Radical Mastectomy. Pain Physician. 2019; 22(4): E315- E323.
67. Qiu Z, He Y, Ming H, Lei S, Leng Y, Xia ZY. Lipopolysaccharide (LPS) Aggravates High Glucose- and Hypoxia/Reoxygenation-Induced Injury through Activating ROS-Dependent NLRP3 Inflammasome-Mediated Pyroptosis in H9C2 Cardiomyocytes. J Diabetes Res. 2019; 2019: 8151836.
68. Hou J, Shen Q, Wan X, Zhao B, Wu Y, Xia Z.REM sleep deprivation-induced circadian clock gene abnormalities participate in hippocampal-dependent memory impairment by enhancing inflammation in rats undergoing sevoflurane inhalation.Behav Brain Res. 2019; 364:167-176.
69. Li Q, Cui S, Jing G, Ding H, Xia Z, He X.The role of PI3K/Akt signal pathway in the protective effects of propofol on intestinal and lung injury induced by intestinal ischemia/ reperfusion1.Acta Cir Bras. 2019; 34(1):e20190010000005.
70. Jia Q, Tian F, Duan WN, Jia YF, Wang HX, Xia ZY. Effects of Dezocine- Remifentanil Intravenous Anaesthesia on Perioperative Signs, Serum TNF-&aipha; and IL-6 in Liver Cancer Patients undergoing Radiofrequency Ablation. J Coll Physicians Surg Pak. 2019; 29(1): 4-7.
71. Shi S, Lei S, Tang C, Wang K, Xia Z. Melatonin attenuates acute kidney ischemia/reperfusion injury in diabetic rats by activation of the SIRT1/Nrf2/HO-1 signaling pathway. Biosci Rep. 2019; 39(1). pii: BSR20181614.
72. Ye JS, Chen L, Lu YY, Lei SQ, Peng M, Xia ZY.SIRT3 activator honokiol ameliorates surgery/anesthesia-induced cognitive decline in mice through anti-oxidative stress and anti-inflammatory in hippocampus. CNS Neurosci Ther. 2019; 25(3):355-366.
73. Ye J, Ding H, Ren J, Xia Z. The publication trend of neuropathic pain in the world and China: a 20-years bibliometric analysis. J Headache Pain. 2018; 19(1):110.
74. Liu L, Yuan Q, Wang Y, Gao W, Hou J, Wu Y, Zhao B, Xia Z. Effects of dexmedetomidine combined with sufentanil on postoperative delirium in young patients after general anesthesia. Med Sci Monit. 2018; 24:8925-8932.
75. Liu L, Zhao B, Xiong X, Xia Z. The Neuroprotective Roles of Sonic Hedgehog Signaling Pathway in Ischemic Stroke. Neurochem Res. 2018; 43(12):2199-2211.
76. Lei S, Zhang Y, Su W, Zhou L, Xu J, Xia ZY. Remifentanil attenuates lipopolysaccharide- induced oxidative injury by downregulating PKCβ2 activation and inhibiting autophagy in H9C2 cardiomyocytes. Life Sci. 2018; 213:109-115.
77. Ye J, Yan H, Xia Z. Oxycodone ameliorates the inflammatory response induced by lipopolysaccharide in primary microglia. J Pain Res. 2018;11:1199-1207.
78. Chen Z, Xu J, Wu Y, Lei S, Liu H, Meng Q, Xia Z. Diosgenin inhibited the expression of TAZ in hepatocellular carcinoma. Biochem Biophys Res Commun. 2018; 503(3):1181-1185.
79. Yang Y, Xia Z, Meng Q, Liu K, Xiao Y, Shi L.Dexmedetomidine relieves neuropathic pain by inhibiting hyperpolarization-activated cyclic nucleotide-gated currents in dorsal root ganglia neurons. Neuroreport. 2018; 29(12):1001-1006.
80. Zhang Y, Su W, Zhang Q, Xu J, Liu H, Luo J, Zhan L, Xia Z, Lei S.Glycine Protects H9C2 Cardiomyocytes from High Glucose- and Hypoxia/Reoxygenation-Induced Injury via Inhibiting PKCβ2 Activation and Improving Mitochondrial Quality. J Diabetes Res. 2018; 2018: 9502895.
81. Wenlan L, Zhongyuan X, Shaoqing L, Liying Z, Bo Z, Min L.MiR-34a-5p mediates sevoflurane preconditioning induced inhibition of hypoxia/reoxygenation injury through STX1A in cardiomyocytes. Biomed Pharmacother. 2018; 102:153-159.
82. Xie HT, Xia ZY, Pan X, Zhao B, Liu ZG. Puerarin ameliorates allodynia and hyperalgesia in rats with peripheral nerve injury. Neural Regen Res. 2018; 13(7):1263-1268.
83. Wu XJ, Liu HM, Song XM, Zhao B, Leng Y, Wang EY, Zhan LY, Meng QT, Xia ZY. Penehyclidine hydrochloride inhibits TLR4 signaling and inflammation, and attenuates blunt chest trauma and hemorrhagic shock-induced acute lung injury in rats. Mol Med Rep. 2018; 17(5): 6327-6336.
84. Tang CL, Li J, Zhang ZT, Zhao B, Wang SD, Zhang HM, Shi S, Zhang Y, Xia ZY. Neuroprotective effect of bispectral index-guided fast-track anesthesia using sevoflurane combined with dexmedetomidine for intracranial aneurysm embolization. Neural Regen Res. 2018; 13(2):280-288.
85. Qiu Y, Wang Y, Wang X, Wang C, Xia ZY. Role of the hippocampal 5-HT1A receptor-mediated cAMP/PKA signalling pathway in sevoflurane-induced cognitive- dysfunction in aged rats. J Int Med Res. 2018; 46(3):1073-1085.
86. Zhao B, Gao WW, Liu YJ, Jiang M, Liu L, Yuan Q, Hou JB, Xia ZY. The role of glycogen synthase kinase 3 beta in brain injury induced by myocardial ischemia/ reperfusion injury in a rat model of diabetes mellitus. Neural Regen Res. 2017; 12(10):1632-1637.
87. Sun Q, Shen ZY, Duan WN, Meng QT, Xia ZY. Mechanism of myocardial ischemia/ reperfusion-induced acute kidney injury through DJ-1/Nrf2 pathway in diabetic rats. Exp Ther Med. 2017;14(5):4201-4207.
88. Meng QT, Chen R, Chen C, Su K, Li W, Tang LH, Liu HM, Xue R, Sun Q, Leng Y, Hou JB, Wu Y, Xia ZY. Transcription factors Nrf2 and NF-κB contribute to inflammation and apoptosis induced by intestinal ischemia-reperfusion in mice. Int J Mol Med. 2017; 40(6): 1731-1740.
89. Tang L, Liu H, Wu Y, Li M, Li W, Jiang M, Hou J, Jiang Y, Xia Z, Meng Q.Sevoflurane may be more beneficial than propofol in patients receiving endoscopic variceal ligation and endoscopic variceal sclerotherapy: A randomized, double-blind study. Exp Ther Med. 2017; 14(4): 3145-3152.
90. Tang C, Xia Z.Dexmedetomidine in perioperative acute pain management: a non-opioid adjuvant analgesic. J Pain Res. 2017;10:1899-1904.
91. Tang C, Li J, Tai WL, Yao W, Zhao B, Hong J, Shi S, Wang S, Xia Z. Sex differences in complex regional pain syndrome type I (CRPS-I) in mice. J Pain Res. 2017;10:1811-1819.
92. Zhang L, Zhou XJ, Zhan LY, Wu XJ, Li WL, Zhao B, Meng QT, Xia ZY. Dexmedetomidine preconditioning protects against lipopolysaccharides-induced injury in the human alveolar epithelial cells. Rev Bras Anestesiol. 2017; S0034-7094 (17): 30410-30415.
93. Gao WW, He ZG, Zhao B, Tang CL, Xiao Y, Jiang M, Xia ZY. Different concentrations of bupivacaine on postoperative urinary retention in patients undergoing subarachnoid anesthesia. Int J Clin Exp Med. 2017; 10(7): 10840-10845.
94. Zhou B, Leng Y, Lei SQ, Xia ZY. AMPK activation restores ischemic post conditioning cardioprotection in STZ induced type 1 diabetic rats: Role of autophagy. Mol Med Rep. 2017; 16(3): 3648-3656.
95. Duan WN, Xia ZY, Liu M, Sun Q, Lei SQ, Wu XJ, Meng QT, Leng Y. Protective effects of SOCS3 overexpression in high glucose induced lung epithelial cell injury through the JAK2/STAT3 pathway. Mol Med Rep. 2017;16(3):2668-2674.
96. Wu Y, Xia ZY, Zhao B, Leng Y, Dou J, Meng QT, Lei SQ, Chen ZZ, Zhu J. (-)- Epigallocatechin-3-gallate attenuates myocardial injury induced by ischemia/reperfusion in diabetic rats and in H9c2 cells under hyperglycemic conditions. Int J Mol Med. 2017; 40(2): 389-399.
97. Xiao Y, Lei S, Huang Y, Zhao B, Wang H, Cao H, Xia Z. Dexmedetomidine protects against renal ischemia and reperfusion injury by inhibiting the P38-MAPK/TXNIP signaling activation in streptozotocin induced diabetic rats. Acta Cir Bras. 2017; 32(6): 429- 439.
98. Gao W, Zhao B, Liu L, Yuan Q, Wu X, Xia Z. Myocardial ischemic post-conditioning protects the lung against myocardial ischemia/reperfusion-induced damage by activating GSK-3β. Acta Cir Bras. 2017; 32(5):376-387.
99. Jiang P, Zhang D, Qiu H, Yi X, Zhang Y, Cao Y, Zhao B, Xia Z, Wang C.Tiron ameliorates high glucose-induced cardiac myocyte apoptosis by PKCδ-dependent inhibition of osteopontin. Clin Exp Pharmacol Physiol. 2017; 44(7):760-770.
100. Zhou B, Lei S, Xue R, Leng Y, Xia Z, Xia ZY. DJ-1 overexpression restores ischaemic post- conditioning-mediated cardioprotection in diabetic rats: role of autophagy. Clin Sci (Lond). 2017; 131(11):1161-1178.
101. Hao W, Zhao ZH, Meng QT, Tie ME, Lei SQ, Xia ZY. Propofol protects against hepatic ischemia/reperfusion injury via miR-133a-5p regulating the expression of MAPK6. Cell Biol Int. 2017; 41(5):495-504.
102. Wu Y, Leng Y, Meng Q, Xue R, Zhao B, Zhan L, Xia Z. Suppression of Excessive Histone Deacetylases Activity in Diabetic Hearts Attenuates Myocardial Ischemia/Reperfusion Injury via Mitochondria Apoptosis Pathway. J Diabetes Res. 2017; 2017:8208065.
103. Zhao ZH, Hao W, Meng QT, Du XB, Lei SQ, Xia ZY. Long non-coding RNA MALAT1 functions as a mediator in cardioprotective effects of fentanyl in myocardial ischemia reperfusion injury. Cell Biol Int. 2017; 41(1):62-70.
104. Huang Y, Xiao Y, Wang H, Wu Y, Sun Q, Xia Z.Toll-like receptor 7 involves the injury in acute kidney ischemia/reperfusion of STZ-induced diabetic rats.Acta Cir Bras.2016;31(7): 448-455.
105. Su W, Zhang Y, Zhang Q, Xu J, Zhan L, Zhu Q, Lian Q, Liu H, Xia ZY, Xia Z, Lei S. N-acetylcysteine attenuates myocardial dysfunction and postischemic injury by restoring caveolin-3/eNOS signaling in diabetic rats. Cardiovasc Diabetol. 2016; 15(1):146.
106. Meng QT, Cao C, Liu HM, Xia ZY, Li W, Tang LH, Chen R, Jiang M, Wu Y, Leng Y, Lee CC. Safety and efficacy of etomidate and propofol anesthesia in elderly patients undergoing gastroscopy: A double-blind randomized clinical study. Exp Ther Med. 2016;12(3):1515-1524.
107. Meng QT, Cao C, Wu Y, Liu HM, Li W, Sun Q, Chen R, Xiao YG, Tang LH, Jiang Y, Leng Y, Lei SQ, Lee CC, Barry DM, Chen X, Xia ZY. Ischemic post-conditioning attenuates acute lung injury induced by intestinal ischemia-reperfusion in mice: role of Nrf2. Lab Invest. 2016; 96(10):1087-1104.
108. Shen ZY, Sun Q, Xia ZY, Meng QT, Lei SQ, Zhao B, Tang LH, Xue R, Chen R. Overexpression of DJ-1 reduces oxidative stress and attenuates hypoxia/reoxygenation injury in NRK-52E cells exposed to high glucose. Int J Mol Med. 2016; 38(3):729-736.
109. Xiao Y, Wu Y, Zhao B, Xia Z. Decreased voltage-gated potassium currents in rat dorsal root ganglion neurons after chronic constriction injury. Neuroreport. 2016; 27(2): 104-109.
110. Chen Z, Liu H, Lei S, Zhao B, Xia Z.LY294002 prevents lipopolysaccharide‑induced hepatitis in a murine model by suppressing IκB phosphorylation. Mol Med Rep.2016;13(1): 811-816.
111. Xue R, Lei S, Xia ZY, Wu Y, Meng Q, Zhan L, Su W, Liu H, Xu J, Liu Z, Zhou B, Xia Z. Selective Inhibition of PTEN Preserves Ischemic Postconditioning Cardioprotection in STZ- induced Type1 Diabetic Rats: Role of the PI3K/Akt and JAK2/STAT3 Pathways. Clin Sci (Lond). 2016;130(5):377-392.
112. Sun Q, Shen ZY, Meng QT, Liu HZ, Duan WN, Xia ZY. The role of DJ-1/Nrf2 pathway in the pathogenesis of diabetic nephropathy in rats. Ren Fail. 2016; 38(2):294-304.
113. Chen Z, Wu Y, Meng Q, Xia Z. Elevated microRNA-25 inhibits cell apoptosis in lung cancer by targeting RGS3. In Vitro Cell Dev Biol Anim. 2016; 52(1):62-67.
114. Li M, Zhou HH, Li T, Li CY, Xia ZY, Duan YY. Polyurethane/poly (vinyl alcohol) hydrogel coating improves the cytocompatibility of neural electrodes. Neural Regen Res. 2015; 10(12): 2048-2053.
115. Gu J, Qin W, Chen F, Xia Z. Long-Term Stability of Tramadol and Ketamine Solutions for Patient-Controlled Analgesia Delivery. Med Sci Monit. 2015; 21: 2528-2534.
116. Chen MQ, Xia ZY.Effect of Concentration on Median Effective Dose (ED50) for Motor Block of Intrathecal Plain Bupivacaine in Elderly Patients. Med Sci Monit. 2015; 21:2588-2594.
117. Yang YC, Meng QT, Pan X, Xia ZY, Chen XD. Dexmedetomidine produced analgesic effect via inhibition of HCN currents. Eur J Pharmacol. 2014; 740:560-564.
118. Xu J, Li H, Irwin MG, Xia ZY, Mao X, Lei S, Wong GT, Hung V, Cheung CW, Fang X, Clanachan AS, Xia Z. Propofol Ameliorates Hyperglycemia-Induced Cardiac Hypertrophy and Dysfunction via Heme Oxygenase-1/Signal Transducer and Activator of Transcription 3 Signaling Pathway in Rats. Crit Care Med. 2014; 42(8):e583-594.
119. Sun Q, Meng QT, Jiang Y, Liu HM, Lei SQ, Su WT, Duan WN, Wu Y, Xia Z, Xia ZY. Protective Effect of Ginsenoside Rb1 against Intestinal Ischemia-Reperfusion Induced Acute Renal Injury in Mice. PLoS One. 2013; 8(12):e80859.
120. Wu X, Song X, Li N, Zhan L, Meng Q, Xia Z. Protective effects of dexmedetomidine on blunt chest trauma-induced pulmonary contusion in rats. J Trauma Acute Care Surg. 2013; 74(2): 524-530.
121. Wu XJ, Xia ZY, Wang LL, Luo T, Zhan LY, Meng QT, Song XM. Effects of penehyclidine hydrochloride on pulmonary contusion from blunt chest trauma in rats. Injury. 2012; 43(2): 232-236.
122. Sun Q, Meng QT, Jiang Y, Xia ZY.Ginsenoside Rb1 attenuates intestinal ischemia reperfusion induced renal injury by activating Nrf2/ARE pathway. Molecules. 2012; 17(6):7195-7205.
123. Meng QT, Xia ZY, Luo Tao, Cao C, Zhao B, Wu Y, Wu XJ, Chen XD. Ligustrazine attenuates acute lung injury induced by blunt chest trauma. Saudi Med. 2012; 33(2): 139-145.
124. Meng QT, Xia ZY, Luo T, Wu Y, Tang LH, Zhao B, Chen JH, Chen X. Dexmedetomidine reduces emergence agitation after tonsillectomy in children by sevoflurane anesthesia: A case-control study. Int J Pediatr Otorhinolaryngol. 2012; 76(7):1036-1041.
125. Zhao B, Xia ZY, Gao WW, Hou JB, Wu Y.Ischemic postconditioning enhances glycogen synthase kinase-3beta phosphorylation and alleviate cerebral ischemia reperfusion injury. Neural Regen Res. 2012;7(19):1507-1512.
126. Hou JB, Xia ZY, Xiao XP, Wan X, Zhao B. Neurotoxicity of intrathecal injections of dexmedetomidine into the rat spinal dorsal horn. Neural Regen Res. 2012; 7(23):1765-1770.
127. Wu Y, Xia ZY, Dou J, Zhang L, Xu JJ, Zhao B, Lei S, Liu HM. Protective effect of ginsenoside Rb1 against myocardial ischemia/reperfusion injury in streptozotocin-induced diabetic rats. Mol Biol Rep. 2011; 38(7): 4327-4335.
128. Xia ZY, Gao J, Ancharaz AK, Liu KX, Xia Z, Luo T. Ischaemic post-conditioning protects lung from ischaemia-reperfusion injury by up-regulation of haeme oxygenase-1. Injury. 2010; 41(5): 510-516.
129. Xia ZY, Wang XY, Chen X, Xia Z. Effect of NO donor sodium nitroprusside on lipopolysaccharide induced acute lung injury in rats. Injury. 2007; 38(1):53-59.
130. Xia ZY, Liu XY, Zhan LY, He YH, Luo T, Xia Z. Ginsenosides compound (shen-fu) attenuates gastrointestinal injury and inhibits inflammatory response after cardiopulmonary bypass in patients with congenital heart disease. J Thorac Cardiovasc Surg. 2005; 130(2):258-264.
中华系列期刊论文
1. 张羽茜, 赵晓帅, 田浩, 邱珍, 雷少青, 夏中元. 毛蕊花苷对小鼠异位心脏移植冷缺血再灌注损伤的影响：与NF-κB/NLRP3信号通路的关系. 中华麻醉学杂志. 2023; 43(10): 1214-1219.
2. 赵晓帅, 张羽茜, 田浩, 李璐, 邱珍, 夏中元. 双侧颈上交感神经节在小鼠心肌缺血再灌注损伤中的作用：与NLRP3炎症小体的关系. 中华麻醉学杂志. 2023; 43(5): 607-612.
3. 李璐, 邱珍, 田浩, 雷少青, 夏中元. SR9009对内毒素血症小鼠心肌损伤的影响. 中华麻醉学杂志. 2023; 43(3): 346-349.
4. 张羽茜, 钟鹏, 李亚男, 王宜飞, 夏中元. 冷诱导RNA结合蛋白在心肌缺血再灌注小鼠急性肾损伤中的作用：与NF-κB信号通路的关系. 中华麻醉学杂志. 2023; 43(3):336-340.
5. 余愿, 侯家保, 刘旭珂, 陈丽丽, 万杏, 夏中元. 海马REV-ERBα在大鼠术后认知功能障碍中的作用. 中华麻醉学杂志. 2022; 42(9): 1059-1063.
6. 李冰玉, 高文蔚, 李亚男, 刘恋, 夏中元. 小鼠脑缺血再灌注早期cGAS-STING信号通路与铁自噬的关系. 中华麻醉学杂志. 2022; 42(8): 953-956.
7. 李璐, 邱珍, 田浩, 夏中元. 糖尿病大鼠心肌缺血再灌注时Rev-erbα与NLRP3炎症小体的关系. 中华麻醉学杂志. 2022; 42(5): 542-545.
8. 黄琴, 田立群, 赵晓帅, 夏中元. 铁死亡在高脂高糖心肌细胞缺氧复氧损伤中的作用.中华麻醉学杂志. 2022; 42(1): 82-87.
9. 陶洁, 熊永红, 田浩, 夏中元. 磷酸甘油酸变位酶5在糖尿病大鼠心肌缺血再灌注损伤中的作用：与线粒体质量的关系. 中华麻醉学杂志. 2021; 41(11): 1382-1386.
10. 明婷倩, 吴晓静, 王倩, 孔倩, 袁敏, 陈丽丽, 夏中元. TIPE2在脓毒症小鼠急性肺损伤内源性保护机制中的作用：与TAK1/p38MAPK/NF-κB信号通路的关系. 中华麻醉学杂志. 2021; 41(11): 1374-1377.
11. 吴科帆, 张爱宁, 邱珍, 江梦, 夏中元. 蛋白质O-GlcNAc修饰在氧糖剥夺/复氧复糖小鼠神经细胞氧化应激损伤中的作用. 中华麻醉学杂志. 2021; 41(11):1396-1399.
12. 邱珍, 李璐, 赵博, 雷少青, 夏中元. HDAC3在原代大鼠心肌细胞高糖缺氧复氧损伤中的作用：与自噬的关系. 中华麻醉学杂志. 2021; 41(10): 1252-1255.
13. 熊永红, 陶洁, 田浩, 李维, 冷燕, 李文远, 张丽琼, 夏中元. TBK1过表达对小鼠高糖离体心肌细胞缺氧复氧损伤的影响：与线粒体自噬的关系. 中华麻醉学杂志. 2021; 41(8): 996-999.
14. 陶洁, 熊永红, 田浩, 田立群, 张艺, 夏中元. Notch1/Hes1信号通路在高糖心肌细胞缺氧复氧损伤中的作用. 中华麻醉学杂志. 2021; 41(4): 450-454.
15. 吴科帆, 张爱宁, 季烨龙, 张艺, 江梦, 夏中元. PERK途径内质网应激与右美托咪定减轻小鼠脑缺血再灌注损伤的关系. 中华麻醉学杂志. 2021; 41(5): 546-550.
16. 田立群, 黄琴, 陶洁, 田浩, 夏中元. HIF-1α在糖尿病大鼠心肌缺血再灌注诱发肾损伤中的作用：与SLC7A11的关系. 中华麻醉学杂志. 2021; 41(5): 593-597.
17. 张爱宁, 吴科帆, 张艺, 季烨龙, 熊永红, 冷燕, 夏中元. 高糖致心肌微血管内皮细胞损伤时SIRT1与STAT3乙酰化的关系. 中华麻醉学杂志. 2021; 41(3): 291-294.
18. 何旋, 吴晓静, 陈鹤翔, 孔倩, 袁敏, 明婷倩, 夏中元. 艾司氯胺酮对内毒素性急性肺损伤大鼠肺组织细胞焦亡的影响. 中华麻醉学杂志. 2021; 41(3): 331-334.
19. 田浩, 熊永红, 张艺, 陶洁, 李璐, 夏中元. NRF2在糖尿病大鼠心肌缺血再灌注损伤中的作用：与铁死亡的关系. 中华麻醉学杂志. 2021; 41(3): 348-352.
20. 邱珍, 张艺, 明浩, 雷少青, 夏中元. Rev-erbα/Bmal1信号通路在糖尿病大鼠心肌缺血再灌注损伤中的作用及其与自噬的关系. 中华麻醉学杂志. 2021; 41(2): 234-238.
21. 石中煜, 熊永红, 李冰玉, 夏中元. 自噬在右美托咪定减轻大鼠高糖离体心肌细胞缺氧复氧损伤中的作用.中华麻醉学杂志. 2021; 41(2): 242-245.
22. 肖兴鹏, 郭明, 马岚, 李思琦, 何旋, 肖业达, 夏中元. 瑞马唑仑-丙泊酚-舒芬太尼用于无痛胃镜检查术患者麻醉的效果. 中华麻醉学杂志. 2021; 41(2): 192-194.
23. 陈鹤翔, 吴晓静, 何旋, 冷燕, 陈丽丽, 张艺, 夏中元. 艾司氯胺酮对脓毒症大鼠心肌损伤的影响及其与Nrf2/HO-1信号通路的关系. 中华麻醉学杂志. 2021; 41(2): 217-220.
24. 季烨龙, 吴洋, 冷燕, 张艺, 张爱宁, 夏中元. c-Abl在糖尿病大鼠心肌缺血再灌注损伤中的作用. 中华麻醉学杂志. 2020; 40(5): 572-576.
25. 刘旭珂, 侯家保, 吴洋, 赵博, 陈丽丽, 刘恋, 夏中元. 海马组蛋白脱乙酰基酶在大鼠PND中的作用及其与PSD95的关系. 中华麻醉学杂志. 2020; 40(8): 929-932.
26. 张艺, 邱珍, 明浩, 季烨龙, 夏中元. 糖尿病大鼠心肌缺血再灌注时SIRT1与NLRP3炎症小体的关系. 中华麻醉学杂志. 2020;40(4):421-424.
27. 陈丽丽, 张元, 苏娃婷, 雷少青, 夏中元. 甘氨酸通过上调糖尿病大鼠心肌小窝蛋白3/内皮型一氧化氮合酶减轻氧化应激损伤. 中华糖尿病杂志. 2020;12(6):404-408.
28. 梅胜兰, 夏中元, 吴晓静, 雷少青, 孟庆涛, 邱珍, 周斌, 明浩, 周金剑. Nrf2-Gpx4信号通路在参麦注射液减轻大鼠心肌缺血再灌注损伤中的作用：与铁死亡的关系. 中华麻醉学杂志. 2019; 39(11): 1395-1398.
29. 明浩, 邱珍, 夏中元, 雷少青, 赵博. HDAC3在心肌缺血再灌注诱发糖尿病大鼠肾损伤中的作用. 中华麻醉学杂志. 2019; 39(8): 993-995.
30. 刘颖, 夏中元, 刘康, 江梦. 内质网应激/蛋白激酶样内质网激酶/DNA损伤诱导因子153通路在七氟烷致大鼠海马神经元细胞凋亡中的作用. 中华实验外科杂志. 2019; 36(9): 1618-1621.
31. 熊永红, 李维, 冷燕, 李文远, 夏中元. 自噬在Parkin过表达减轻糖尿病大鼠心肌肥厚中的作用. 中华麻醉学杂志. 2019; 39(5): 613-616.
32. 施思, 雷少青, 刘慧敏, 赵博, 夏中元. 酪醇对糖尿病大鼠心肌缺血再灌注损伤的影响及SIRT1/AMPK/eNOS信号通路在其中的作用. 中华麻醉学杂志. 2019; 39(5): 552-555.
33. 李灵丰, 吴晓静, 孔倩, 袁敏, 赵桂华, 邱珍, 黄琴, 夏中元. 右美托咪定对胸部撞击-失血性休克复苏致大鼠急性肺损伤时NLRP3炎症小体的影响. 中华麻醉学杂志. 2019; 39(6): 754-757.
34. 刘颖, 夏中元, 张振, 徐阳. 海马神经细胞端粒酶反转录酶在七氟烷干预下的表达及对细胞凋亡的影响. 中华实验外科杂志. 2019; 36(2): 277-278.
35. 黄琴, 夏中元, 雷少青, 冷燕, 施思, 邱珍, 王凯. 糖尿病心肌损伤与酪蛋白激酶CK1ε参与调控的时钟基因Per2的关系. 中华糖尿病杂志. 2019; 11(4): 276-281.
36. 袁泉, 赵博, 刘恋, 侯家保, 唐朝亮, 夏中元. 自噬在糖尿病小鼠脑缺血再灌注损伤中的 作用：与HDAC3/Bmal1信号通路的关系. 中华麻醉学杂志. 2018; 38(11): 1380-1383.
37. 靖国庆, 吴云, 孟庆涛, 王鄂友, 夏中元.羟考酮预处理对于大鼠肠缺血再灌注时线粒体途径肝细胞凋亡的影响. 中华麻醉学杂志. 2018; 38(6): 672-675.
38. 肖业达, 曹红, 赵博, 黄亚医, 汪华新, 夏中元. TXNIP/NLRP3信号通路在糖尿病大鼠肾缺血再灌注损伤中的作用. 中华麻醉学杂志. 2018; 38(1): 74-77.
39. 邱珍, 夏中元, 雷少青, 赵博, 吴洋. NLRP3炎症小体在糖尿病大鼠心肌缺血再灌注时细胞焦亡中的作用. 中华麻醉学杂志. 2018; 38(6): 732-735.
40. 靖国庆, 吴云, 孟庆涛, 王鄂友, 夏中元. mAb2G4-ODN-lip对大鼠心肌缺血再灌注损伤的影响. 中华麻醉学杂志. 2018; 38(5): 614-617.
41. 谢景远, 刘永芳, 彭璇, 刘志刚, 孟庆涛, 夏中元. 改良穿刺法与传统穿刺法在锁骨下静脉穿刺术中应用效果的比较. 中华解剖与临床杂志. 2018; 23 (2): 143-147.
42. 李维, 冷燕, 孟庆涛, 吴洋, 陈榕, 刘慧敏, 夏中元. Ⅰ型组蛋白去乙酰化酶在糖尿病大鼠心肌缺血再灌注损伤中的作用及其与AMPK/mTOR信号通路的关系. 中华麻醉学杂志. 2018; 38(7): 808-812.
43. 侯家保, 沈倩妮, 万杏, 赵博, 吴洋, 夏中元. 急性睡眠剥夺对七氟烷麻醉大鼠学习记忆及海马时钟基因表达的影响. 中华行为医学与脑科学杂志. 2018; 27(7): 577-581.
44. 曾诚, 夏中元, 孙倩, 肖业达. 叔丁基对苯二酚对糖尿病大鼠肾缺血再灌注时DJ-1/Nrf2通路的影响. 中华麻醉学杂志. 2018; 38(7): 870-873.
45. 刘恋, 赵博, 冷燕, 吴洋, 高文蔚, 夏中元. Akt/GSK-3β信号通路在曲古霉素A减轻小鼠脑缺血再灌注损伤中的作用. 中华麻醉学杂志. 2018; 38(9): 1137-1140.
46. 崔淑侠, 王彩霞, 段启瑞, 夏中元. 不同剂量黄芪对肺栓塞大鼠血清和肺组织血管内皮生长因子和碱性成纤维细胞生长因子水平的影响. 中华麻醉学杂志. 2018; 38(9): 1150-1152.
47. 沈倩妮, 侯家保, 赵博, 吴洋, 刘恋, 孟庆涛, 夏中元. 七氟醚对睡眠剥夺大鼠视交叉上核Egr-1和Egr-2表达的影响. 中华麻醉学杂志. 2017; 37(9): 1102-1104.
48. 孔倩, 吴晓静, 张蕾, 赵博, 江莹, 孟庆涛, 詹丽英, 王鄂友, 夏中元. 小窝蛋白-1在盐酸戊乙奎醚抑制LPS诱导小鼠巨噬细胞TLR4/p38MAPK信号通路激活中的作用. 中华麻醉学杂志. 2017; 37(9): 1132-1135.
49. 冷燕, 吴洋, 赵博, 雷少青, 刘敏, 侯家保, 夏中元. SIRT1介导糖尿病大鼠心肌线粒体自噬的机制与Mfn2的关系. 中华麻醉学杂志. 2017; 37(8): 993-996.
50. 刘焱伟, 薛锐, 夏中元, 孟庆涛, 李维, 冷燕, 周斌. 第10号染色体丢失性磷酸酶及张力蛋白同源基因调控的酪氨酸蛋白激酶2_信号传导与转录因子3信号通路对糖尿病心肌缺血后处理敏感性的作用. 中华糖尿病杂志. 2017; 9(8): 515-519.
51. 刘康, 夏中元, 赵博, 周芳, 肖昀, 侯家保. 右美托咪定对糖尿病神经痛大鼠脊髓P2X4/ NLRP3通路的影响. 中华麻醉学杂志. 2017; 37(5): 536-539.
52. 郭明, 赵博, 雷少青, 邱珍, 吴洋, 夏中元. Sestrin2/一磷酸腺苷活化的蛋白激酶介导的细胞自噬在糖尿病大鼠心肌缺血再灌注损伤中的作用及叔丁基对苯二酚预处理的保护作用. 中华糖尿病杂志. 2017; 9(6): 382-387.
53. 余艳丽, 夏中元, 方海滨, 周斌, 雷少青. DHA调节人脑血管周细胞氧糖剥夺-复氧复糖时血管生成素表达的机制:与SSeCKS的关系. 中华麻醉学杂志. 2017; 37(2): 188-191.
54. 梁启恒, 夏中元, 苏娃婷, 赵博, 张琼霞, 张元, 雷少青. N-乙酰半胱氨酸对糖尿病大鼠心肌缺血再灌注损伤时Cav-3表达的影响. 中华麻醉学杂志. 2017; 37(2): 224-226.
55. 薛锐, 夏中元, 雷少青, 赵博, 孟庆涛, 李维, 周斌. PTEN在糖尿病因素削弱缺氧后处理对心肌细胞保护效应中的作用：与GSK-3β介导的线粒体凋亡途径的关系. 中华麻醉学杂志. 2017; 37(1):108-111.
56. 陈小波, 余艳丽, 方海滨, 夏中元. 二十二碳六烯酸对大鼠氧糖剥夺脑微血管内皮细胞Ang-2和VEGF表达的影响. 中华麻醉学杂志. 2016; 36(9): 1142-1145.
57. 潘雪莲, 赵博, 肖昀, 侯家保, 夏中元. 新生期不同时间七氟醚麻醉对大鼠远期认知功能和海马突触可塑性的影响. 中华麻醉学杂志. 2016; 36(9): 1085-1088.
58. 周斌, 夏中元, 吴洋, 刘敏, 孙倩. 一磷酸腺苷活化蛋白激酶调控的自噬作用可恢复糖尿病心肌对缺血后处理的敏感性. 中华糖尿病杂志. 2016; 8(12): 751-757.
59. 周斌, 夏中元, 赵博, 孙倩, 薛锐, 刘敏. 缺氧后处理对糖尿病性心肌细胞缺氧复氧时保护作用削弱的机制：与DJ-1表达的关系. 中华麻醉学杂志. 2016; 36(4): 495-497.
60. 刘敏, 汪华新, 赵博, 肖业达, 刘康, 夏中元. 大鼠急性高糖对肾缺血再灌注损伤的影响及右美托咪定预处理的保护作用. 中华实验外科杂志. 2016; 33(6): 1485-1487.
61. 张元, 夏中元, 苏娃婷, 雷少青. N-乙酰半胱氨酸对糖尿病大鼠肺组织氧化应激及p22phox表达的影响. 中华糖尿病杂志. 2016; 8(3): 168-171.
62. 赵博, 冷燕, 吴晓静, 侯家保, 吴洋, 夏中元. JAK2/STAT3信号通路在糖尿病大鼠心肌缺血再灌注诱发脑损伤中的作用. 中华麻醉学杂志. 2016; 36(2): 211-213.
63. 肖昀, 赵博, 吴洋, 侯家保, 夏中元. 鞘内注射U0126对紫杉醇诱导外周神经痛大鼠背根神经节Nav1.7蛋白表达的影响. 中华实验外科杂志. 2016; 33(5): 1295-1297.
64. 吴晓静, 高文蔚, 冷燕, 赵博, 孟庆涛, 詹丽英, 夏中元. 盐酸戊乙奎醚对胸部创伤-失血性休克复苏致大鼠急性肺损伤时Fas/FasL表达的影响. 中华麻醉学杂志. 2015; 35(9): 1138-1141.
65. 沈孜颖, 夏中元, 孙倩, 赵博, 孟庆涛, 雷少青. DJ-1/Nrf2通路对高糖诱导大鼠肾小管上皮细胞损伤的保护作用. 中华实验外科杂志. 2015; 32(12): 2993-2995.
66. 杨颖聪, 陈向东, 夏中元. 脊髓HCN通道在右美托咪定抗伤害效应中的作用：在体和离体实验. 中华麻醉学杂志. 2015; 35(9): 1096-1100.
67. 李文澜, 夏中元, 孙倩, 赵博, 江莹, 詹丽英. 人参皂苷Rb1对肠缺血再灌注致肾损伤的影响及其机制. 中华实验外科杂志. 2015; 32(11): 2715-2717.
68. 杨定东, 夏中元, 张晶晶, 张宣. 超声引导近端筋膜间闭孔神经阻滞的效果. 中华麻醉学杂志. 2015; 35(7): 840-843.
69. 吴晓静, 冷燕, 高文蔚, 赵博, 薛锐, 詹丽英, 夏中元. 盐酸戊乙奎醚对胸部创伤-失血性休克复苏致大鼠急性肺损伤时NF-κB和AP-1活性的影响. 中华麻醉学杂志. 2015; 35(6): 751-754.
70. 刘敏, 夏中元, 赵博, 吴洋, 薛锐, 冷燕. DJ-1与糖尿病因素影响大鼠缺血后处理心肌保护作用的关系. 中华麻醉学杂志. 2015; 35(5): 539-542.
71. 陈小波, 夏中元, 雷凡, 薛锐. 二十二碳六烯酸预处理增强血管生成素对氧糖剥夺条件下大鼠脑微血管内皮细胞的保护作用. 中华临床营养杂志. 2015; 23(2): 103-109.
72. 吴晓静, 冷燕, 赵博, 江莹, 夏中元, 孟庆涛, 詹丽英. 盐酸戊乙奎醚对胸部撞击一失血性休克/复苏致大鼠急性肺损伤的影响. 中华麻醉学杂志. 2014; 34(9): 1112-1115.
73. 江梦, 吴晓静, 夏中元, 薛锐, 刘珍珍, 孟庆涛. 炎性反应在胸部撞击和胸部撞击-失血性休克复苏致大鼠急性肺损伤中作用的比较. 中华麻醉学杂志. 2014; 34(4): 497-499.
74. 赵博, 夏中元, 高文蔚, 刘敏, 吴洋. 缺血后处理对糖尿病大鼠心肌缺血再灌注诱发脑损伤的影响. 中华麻醉学杂志. 2014; 34(1): 82-84
75. 吴晓静, 段薇娜, 薛锐, 夏中元, 赵博. TLR4/NF-κB信号通路在胸部撞击和胸部撞击-失血性休克复苏致大鼠急性肺损伤中作用的比较. 中华麻醉学杂志. 2014; 34(2): 233-236
76. 高文蔚, 赵博, 詹丽英, 吴晓静, 夏中元. 心肌缺血再灌注致急性肺损伤机制与后处理保护效应. 中华创伤杂志. 2014; 30(6): 594-597.
77. 姚瑶, 夏中元, 刘珍珍, 吴洋, 赵博. 糖尿病大鼠心肌缺血再灌注时DJ-1蛋白表达的变化. 中华麻醉学杂志. 2013; 33(6): 661-664.
78. 赵博, 高文蔚, 侯家保, 刘敏, 夏中元. 缺血后处理减轻心肌缺血再灌注引起的脑损伤的机制.中华实验外科杂志. 2013; 30(11): 2352-2354.
79. 高文蔚, 夏中元, 赵博, 刘敏, 侯家保, 罗涛. 监测脑电双频谱指数预防全麻患者术中知晓的效果:meta分析. 中华麻醉学杂志. 2013; 33(6): 691-693
80. 杜立, 詹丽英, 夏中元, 孟庆涛,吴晓静. 肺组织γ-氨基丁酸A型受体在大鼠内毒素诱发急性肺损伤中的作用. 中华麻醉学杂志. 2012; 32(10): 1275-1277.
81. 吴洋, 夏中元, 赵博, 侯家保, 孟庆涛, 刘慧敏. PI3K/Akt信号转导通路在人参皂苷Rb1预先给药减轻糖尿病大鼠心肌缺血再灌注损伤中的作用. 中华麻醉学杂志. 2012; 32(3): 358-360.
82. 江莹, 夏中元, 高瑾, 徐金金, 孟庆涛, 侯家保. 缺血后处理对大鼠缺血-再灌注肺损伤血红素加氧酶-1表达的影响. 中华急诊医学杂志. 2012; 21(10): 1122-1126.
83. 杨进国, 夏中元, 赵博, 江莹, 胡兴云, 孟庆涛. 人参皂甙Rb1在核因子NF-E2相关因子2/血红素氧合酶-1通路减轻肠缺血再灌注致急性肺损伤中的分子机制. 中华实验外科杂志. 2012; 29(11): 2234-2236.
84. 孟庆涛, 孙倩, 江莹, 吴洋, 李维, 唐玲华, 夏中元. 缺血后处理对小鼠肠缺血再灌注致肾损伤时Nrf2蛋白表达的影响. 中华麻醉学杂志. 2012; 32(4): 504-507.
85. 詹丽英, 赵博, 夏中元. 缺血后处理减轻脑皮质缺血-再灌注损伤. 中华急诊医学杂志. 2012; 21(2): 171-174.
86. 刘志刚, 陈向东, 刘永芳, 赵博, 杜立, 罗涛, 夏中元. 缝隙连接在大鼠异丙酚和七氟醚麻醉中的作用. 中华麻醉学杂志. 2011; 31(6): 684-686.
87. 侯家保, 肖兴鹏, 夏中元, 赵博, 吴洋. 鞘内注射不同剂量右美托咪定对大鼠的抗伤害效应和脊髓神经毒性. 中华麻醉学杂志. 2011; 31(6): 710-713.
88. 吴晓静, 李宁涛, 夏中元, 王伶俐. 盐酸戊乙奎醚对大鼠胸部撞击致急性肺损伤及肺组织Toll样受体4表达的影响. 中华麻醉学杂志. 2011; 31(6): 750-753.
89. 王伶俐, 夏中元, 吴晓静, 詹丽英. 盐酸戊乙奎醚对大鼠创伤性急性肺损伤时细胞凋亡的影响. 中华麻醉学杂志. 2011; 31(4): 494-496.
90. 李宁涛, 吴晓静, 夏中元. 右美托咪定对大鼠胸部撞击性肺损伤血清肿瘤坏死因子-α和白介素-1β的影响. 中华急诊医学杂志. 2011; 20(5): 485-488.
91. 张力, 夏中元, 吴洋, 库玛. 一氧化氮在人参皂甙Rb1预处理减轻糖尿病大鼠心肌缺血再灌注损伤中的作用. 中华麻醉学杂志. 2010; 30(10): 1168-1171.
92. 赵博, 夏中元, 高文蔚, 侯家保, 吴洋, 高鸿, 吴长健. 缺血预处理和缺血后处理对大鼠脑缺血再灌注时糖原合酶激酶-3β活性的影响. 中华麻醉学杂志. 2010; 30(11): 1391-1393.
93. 詹丽英, 夏中元, 夏芳, 刘先义. p38MAPK/iNOS/HO-1信号通路在赤芍减轻大鼠内毒素性急性肺损伤中的作用. 中华麻醉学杂志. 2009; 29(3): 258-261.
94. 夏中元, 江梦, 肖业达, 孟庆涛. 参附注射液对糖尿病大鼠心肌缺血再灌注时PTEN和P13 K表达的影响. 中华麻醉学杂志, 2009, 29(6) 490-493.
95. 罗凤芹, 周青山, 刘先义, 夏中元. 异丙酚对脊髓缺血再灌注损伤大鼠脊髓细胞凋亡的影响. 中华麻醉学杂志. 2006; 26(4): 372-375.
96. 夏中元, 王晓园, 杜大平, 刘先义. 硝普钠对内毒素致大鼠急性肺损伤保护作用的机制. 中华麻醉学杂志. 2006; 26(2): 148-151.
97. 夏中元, 陈畅, 王晓圆. 赤芍对内毒素性急性肺损伤大鼠肺诱导型血红素氧化酶和诱导型一氧化氮合酶表达的影响. 中华创伤杂志. 2005; 21(9): 675-678.
98. 夏中元, 罗涛, 夏芳, 刘先义, 黄海波. 生脉注射液对肠粘膜再灌注损伤保护作用机制的实验研究. 中华麻醉学杂志. 2001; 21(5): 299-301.
99. 夏中元, 郑利民. 参附注射液防护肠黏膜缺血再灌注损伤的实验研究. 中华创伤杂志. 2001; 17(4): 235-236.
100. 夏中元, 郑利民, 刘莉, 何宇红. 生脉注射液对失血性休克复苏时肠粘膜的保护作用. 中华实验外科杂志. 2001; 12(18)增: 79-80.
101. 郑利民, 夏中元. 失血性休克再灌注时肠粘膜内pH与肠粘膜组织学改变的相关性. 中华麻醉学杂志. 2000; 20(12): 774.
102. 夏中元, 郑利民. 罗库溴铵合用阿曲库铵时肌松效应及不良反应. 中华麻醉学杂志. 1999; 19(5):314.
103. 夏中元, 刘颖涛, 万德宁. 几种不同药物对大鼠全脑缺血再灌注时大脑c-fos基因表达影响的实验研究. 中华麻醉学杂志. 1996; 11(16):554-556.
科研项目
1. PTEN/PI-3K/Akt信号通路在糖尿病心肌再灌注损伤中作用及分子机制; 2007 国家自然科学基金 面上项目 主持，2007-01-01至2009-12-31 , 28
2. DJ-1介导的信号通路在糖尿病心肌缺血/再灌注损伤中的作用和分子机制; 2011 国家自然科学基金面上项目 主持，2012-01-01至2015-12-31 , 62
3. Parkin/DJ-1调控的线粒体自噬在恢复糖尿病心肌对缺血后处理敏感性中的作用及机制; 2015 国家自然科学基金 面上项目 主持，2015-01-01至2018-12-31 , 72
4. NcoR1-HDAC3/BMAL1介导的线粒体自噬节律紊乱在糖尿病心肌再灌注易损性增加中的作用及机制；2017 国家自然科学基金 面上项目 主持，2017-01-01至2020-12-31 , 58
5. REV-ERBa振荡调控的铁死亡在糖尿病心肌再灌注易损性增加中的作用及机制；2019 国家自然科学基金 面上项目 主持，2020-01-01至2023-12-31 , 53
6. 失神经支配对线粒体氧化还原节律紊乱的影响及其在移植心脏再灌注损伤加重中的作用；2021 国家自然科学基金 面上项目 主持， 2022-01-01至2025-12-31 , 55
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参编书籍
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5. 吸入麻醉临床实践，编委，2015.08出版，人民卫生出版社
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7. 麻醉学进展【2017】、麻醉学进展【2018】、麻醉学进展【2019】、麻醉学进展【2020】 麻醉学进展【2021】，编委，2018.10出版，中华医学电子音像出版社
8. Textbook of Anesthesiology and Perioperative Medicine，编委，2018.10出版，人民卫生出版社
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